These symptoms may suggest inadequate B12 replacement, concurrent iron or folate deficiency, or alternative haematological conditions requiring investigation
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Age-related changes in gastric function can reduce food-bound B12 absorption whilst synthetic supplement absorption remains adequate
While biotin deficiency is relatively uncommon, individuals with certain metabolic conditions, those taking long-term medications such as anticonvulsants, or patients with poor nutritional absorption may benefit from intramuscular administration
For finer dose control, add 3 mL instead of 2 mL, producing a 3.33 mg/mL concentration
Excessive intake is generally unnecessary