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Moreover, PGC-1 activator ZLN005 mitigates renal injury by accelerating mitochondrial clearance in mice with cisplatin-induced AKI, increasing co-localization between LC3 and damaged mitochondria [51]

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Copper is an essential trace element required for numerous enzymatic and structural proteins involved in redox balance, extracellular matrix organisation, and cellular metabolism

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However, most intervention trials of B-vitamin supplementation have found homocysteine lowering does not reduce risk of heart attack