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For multiple myeloma, preclinical data demonstrate synergistic effects when combined with proteasome inhibitors like bortezomib, where resveratrol downregulates Hedgehog signaling components and enhances drug sensitivity in BTZ-resistant cell lines [35]

A new perspective in @Cell_Metabolism from NIH scientists points to a vicious cycle: stiff tissues poor blood flow low cellular energy damaged, inflammatory cells more stiffness

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