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Upon receptor engagement, BPC-157 initiates downstream phosphorylation cascades involving phospholipase C-gamma and protein kinase C activation, measurable through Western blot analysis and fluorescence-based kinase activity assays

52333003 to X.J.), Basic Research Program of Jiangsu (BK20244003) and the Natural Science Foundation of Jiangsu Province (BK20202002)

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In people with insulin resistance or type 2 diabetes, GLP1 and GIP activity can support glucose-dependent insulin secretion, which means insulin release increases mainly when glucose is elevated

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