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Pancreas : GLP-1 receptor activation stimulates glucose-dependent insulin secretion from pancreatic beta cells whilst suppressing inappropriate glucagon release

Phase 1 single (SAD) and multiple ascending dose (MAD) studies of the safety, tolerability, pharmacokinetics (PK) and pharmacodynamics (PD) of FT-4202, an allosteric activator of pyruvate kinase-R, in healthy and sickle cell disease subjects

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