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A new lab study by Po Hien Ear, PhD, and Andrew Bellizzi, MD, along with their team at the University of Iowa and collaborators at the University of Texas MD Anderson Cancer Center, was recently presented at NETRFs 2025 Marie & Robert E

Many people notice reduced appetite within the first few weeks, but meaningful weight loss builds gradually over months as the dose increases

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Decreases in body weight, BMI, and waist circumference Improved insulin sensitivity and blood sugar control Reduced total testosterone levels More regular menstrual cycles and higher rates of natural ovulation Theres also evidence that combining GLP-1s with metformin, a long-standing insulin-sensitizing medication, may amplify these benefits, especially for women whove struggled to lose weight on metformin alone

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