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In addition, a good balance of bile acids and an increase in their secretion are essential

The most common clinical manifestations include urticaria, pruritus, and flushing, often accompanied by mild wheezing or dyspnea, particularly in individuals with asthma or reactive airway disease

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Awareness of these motivations also helps in making informed decisions about whether creatine is safe for 16 year olds in each individual case

J Endourol 1999