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Who Can Benefit Most from B12 Injections

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22,23 In patients with a normal or low-normal serum vitamin B 12 level, complete blood count results demonstrating macrocytosis, or suspected clinical manifestations, a serum methylmalonic acid level is an appropriate next step 1,2,6,18 and is a more direct measure of vitamin B 12 's physiologic activity

People who have ileitis (Crohns disease that affects the ileum) or those who have undergone small bowel surgery might be deficient in (not have enough) vitamin B 12 12

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If your levels were very low, this early phase can feel especially noticeable