FIGURE 3 GO and KEGG analyses of the 59 aforementioned candidate targets indicated that the biological process (BP) terms of the target genes were mainly involved in the positive regulation of cell proliferation (GO:0008284), protein phosphorylation (GO:0006468), positive regulation of cell migration (GO:0030335), and negative regulation of apoptosis (GO:0043066)
These two conditions are closely interrelated, with DM representing a significant risk factor for CVD due to factors such as obesity, hypercholesterolemia, atherosclerosis, microcirculation disorders, and hypertension [1, 2]
& Suddek, G
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under conditions of cytotoxic oxidative stress, Se can prevent cellular damage and the release or exposure of autoantigens as well as reduce the toxic effects of reactive oxygen radicals
American Association of Clinical Endocrinologists and American College of Endocrinology Comprehensive Clinical Practice guidelines for medical care of patients with obesity