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Additionally, 26.5% of participants receiving orlistat achieved at least a 5% reduction in BMI, compared to 15.7% in the placebo group

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No formal tolerance study exists, but neuropeptide receptors can downregulate under sustained stimulation

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"Metastatic melanomas of unknown primary show better prognosis than those of known primary: a systematic review and meta-analysis of observational studies"

Dizziness or lightheadedness Uncommon, and when reported, usually mild and short-lived