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Dietary Reference Intakes for Selenium The IOM has set the RDAs for selenium based on the amount required to maximize the activity of glutathione peroxidases found in blood plasma

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However, an imbalance between ROS production and antioxidant defense mechanisms can lead to oxidative stress, a pathological state linked to diseases like cancer and neurodegeneration [9]

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Sources Bes, F., Jobert, M., Schulz, H., & Saletu, B