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This is further supported by the lack of Bip upregulation, a hallmark feature of ER stress (Fig

Tirzepatide versus insulin glargine in type 2 diabetes and increased cardiovascular risk (SURPASS-4)

10.1056/NEJMoa2031054 184

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Melanoma Sample Selection To test the specificity of this marker, we analyzed different variants of melanomas (desmoplastic/spindle cells melanoma, superficial spreading melanoma (SSM) and nodular melanoma), melanomas at different stages (primary and metastatic), and tested tissue microarray slides, as well as whole-tissue sections (WTS)