She also laments the current limited access to these medications in Brazil, noting that, From a clinical standpoint, broader affordability would represent a major step forward in expanding access to evidence-based obesity and diabetes treatments. For now, she says the message for clinicians is clear: GLP-1RAs are an effective option for managing weight gain and metabolic complications in patients with psychiatric disorders without serious adverse events
Requires indefinite use
J Endocrinol (1991) 130(2):26772
If you have a history of thyroid cancer, pancreatitis, severe diabetic retinopathy, or are pregnant, certain GLP-1 options may be restricted
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Leptin is overexpressed at the gene level in the WAT of individuals with obesity [73]