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The glucagon-like peptide-1 agonists (GLP-1s) class of weight-loss drugs, which includes medications like tirzepatide and semaglutide, have been shown to reduce body fat in large clinical trials
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Hattori Y, Jojima T, Tomizawa A, Satoh H, Hattori S, Kasai K, Hayashi T: A glucagon-like peptide-1 (GLP-1) analogue, liraglutide, upregulates nitric oxide production and exerts anti-inflammatory action in endothelial cells
If you discontinue GLP-1 therapy without maintaining caloric deficit and exercise, facial fat can gradually return as your body replenishes energy stores
It is important to talk with your healthcare provider about these things
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