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Tumour-specific irAEs and clinical outcomes A mechanistic link was proposed by the investigators of a prospective cohort study in which 73 NSCLC patients treated ICI showed that there was shared cancer and tissue antigens and T cell infiltration in both the lung tumour and the skin, suggesting an overlap between the toxicities and the efficacy [44]

These findings further validate the extraordinary antioxidant capacity of G/D-CuP, emphasizing its promise for use in wound repair

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Mitochondrial BCL-2 inhibits AMBRA1-induced autophagy

Furthermore, we did not find differences in demographics between our cases and controls, except that symptomatic controls had a significantly earlier age at menarche