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[15] [16] When used with insulin or sulfonylureas, dose adjustments of these medications may be needed to reduce hypoglycaemia risk

Additionally, the potential for off-target effects, including immune suppression or undesired effects on nonpathogenic cells, may limit the safety of immunotherapy

Since people can react differently to supplements, starting at a low dose will help you gauge your tolerance

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Liss DB, Paden MS, Schwarz ES, Mullins ME

Its always best to start with safe methods like proper hydration, sun protection, and using products with proven brightening ingredients