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In the following decade, long-acting subcutaneous or daily oral GLP-1 receptor agonists administered weekly emerged [7]

Rushing dose increases without establishing baseline response often leads to unnecessary nausea or gastrointestinal discomfort

The largest and longest trial to date includes 320 individuals with biopsy-confirmed NASH and fibrosis randomised to treatment with once-daily semaglutide (0.1 mg, 0.2 mg or 0.4 mg) vs placebo [69]

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Besides, three positive responsive groups demonstrated significant repigmentation of vitiligo lesions and acceptable tolerability with a follow-up period of 52 weeks (35)

Apply a cold compress to the bridge of the nose to promote vasoconstriction