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The significance of glutathione includes several key functions: Antioxidant Defense : It combats oxidative stress by neutralizing free radicals

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For example, G6PD activity and PPP flux were found to be essential for innate immune sensing of Aspergillus infection by Nod-like receptors in airway epithelial cells (17)

Histochemical demonstration of enhanced glutathione content in enzyme-altered islands induced by carcinogens in rat liver

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