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Among those candidates, we selected four enzyme complexes comprising eleven identified targets for further experimental validation based on the availability of suitable inhibitors

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However, liver transplantation may be considered as a second-line option if necessary

In summary, dysregulation of immunoregulatory signalling molecules, including cytokines, microglial complement, MET, and MHCI, is an important link in the pathological process of ASD that possibly regulates synaptic morphology and plasticity in the CNS through common downstream pathways