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When starting semaglutide in a patient on insulin, the basal insulin dose is typically reduced by 10-20% to start, with further reductions as A1c improves

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2018;17(3): e12728

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(Article in Japanese) Sakurabayashi T, Takaesu Y, Haginoshita S, et al

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Increase water, sodium, potassium, and magnesium

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These effects are dose-dependent and typically improve after the first 4 to 8 weeks of treatment

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At 10 mg/ml, 2.5 mg equals 0.25 ml

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