For metabolites for which an internal standard was not present in the extraction mix, external standard libraries were used to perform analysis of relevant metabolite concentrations
Glutathione binds to toxins, heavy metals, and alcohol byproducts, making them water-soluble so they can be flushed out through the bodys natural detoxification processes
Ferroptosis, an atypical type of cell death first reported by Dixon and colleagues in 2012 (2), is fundamentally different from other types of cell death, such as pyroptosis, apoptosis, autophagy, and necroptosis (3, 4)
Protein and mRNA expression of protein kinase C (PKC) in the postmortem brain of bipolar and schizophrenic subjects
While passive diffusion was initially proposed as the main absorption route, recent evidence indicates that specific transmembrane transporters including Na-taurocholate cotransporting polypeptide, organic anion-transporting polypeptides, L-type amino acid transporters, and monocarboxylate transporters also facilitate LT4 uptake
Absence of Gclc impairs mitochondrial respiration in FoB Our data above showed that glucose-derived fluxes into the TCA cycle were reduced in GSH-deficient FoB
