Glucaric acid and ribonic acid had the most significant positive correlation with each other, and there were also highly positive correlations between L-acetylcarnitine and L-carnitine, and between taurine and glutathione (Table 3)
That is, after the initial treatment with injections of B12, dietary supplements of B12 (cyanocobalamin tablets) may be advised instead of injections
Nevertheless, after decades in behavior and lifestyle based longevity medicine, including leading the multidisciplinary intensive lifestyle program at the Pritikin Longevity Center that led to Medicares approval for Pritikins ICR (intensive cardiac rehab - aka heart disease reversal) program, and logging over 20K hrs building comprehensive metabolic health intervention programs (including Henry Ford Health which Reality Meets Science licenses our Flex5 lifestyle change program), one conclusion is clear: The engine is behavioral
Medina-Vera D, Navarro JA, Tovar R, Rosell-Valle C, Gutierrez-Adan A, Ledesma JC, Sanjuan C, Pavon FJ, et al (2021) Activation of PI3K/Akt Signaling Pathway in Rat Hypothalamus Induced by an Acute Oral Administration of D-Pinitol
The presence of free radicals in our body may be due to pollution, dietary choices and other environmental factors
So unprofessional stay away