And we started doing studies, and by, I would say, 2018, 2019, we knew this was going to be the most effective obesity drug weve ever seen
2024 Dec 23;66(1718):201-2 doi:10.58347/tml.2024.1718a Zepbound (tirzepatide) prescribing information
61 Activation of GLP-1 and GIP receptors stimulates insulin secretion from pancreatic beta cells in response to postprandial elevation in plasma glucose, and this effect is markedly attenuated under normoglycemic conditions, thereby mitigating the risk of hypoglycemia associated with GLP-1RAs therapy
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Some patients feel hesitant to mention supplements, fearing their doctor might be dismissive
The combination is being used clinically and reported anecdotally in the research community