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The study was approved by the local research ethics committee with approval code (No: 36264MS83/2/23)

Aquaporin-4 (AQP4), predominantly expressed in astrocytic end-feet, regulates the flux of cerebrospinal fluid, clearance of amyloid-beta, and inflammation [57, 58]

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Tirzepatide treatment was also associated with a reduction in waist circumference, systolic blood pressure, fasting insulin and plasma lipid concentrations as cardiometabolic risk parameters

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Restraints Impact Analysis Regulatory scrutiny of promotion: Authorities are challenging misleading claims about compounded GLP-1 products and product equivalence