3 The BMI threshold is 2.5 lower for people from South Asian, Chinese, other Asian, Middle Eastern, Black African, or African-Caribbean backgrounds, who are at higher risk of weight-related conditions at a lower BMI
Compounded drugs do not undergo the same amount of testing for safety, effectiveness, and quality that FDA-approved drugs do, so they naturally pose a higher risk to people taking them
Confirmed every 36 months to stay within 10 % of the target strength Screened for bacteria, fungi, and other contaminants to meet USP 797 standards Checked to USP 85 limits to ensure zero harmful bacterial toxins Fine-tuned for a smooth, irritation-free injection *Compounded medications may be prescribed by physicians, but have not been FDA-regulated for safety, effectiveness, or quality
Authors contributions Study concept and design (SS, SK), acquisition of data (JV, VS), analysis and interpretation of data (JV, VS, SS, SK), drafting of the manuscript (JV, VS), critical revision of the manuscript for important intellectual content (SS, SK, JS, PM, DN), and study supervision (SS, SK, JS, PM, DN)
In addition, a 2024 study found that people taking another GLP-1 drug, liraglutide, had a 179% higher risk of developing NAION
10.1016/s0899-9007(00)00421-4 38 LarssonA.EngelJ