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Glutathione is readily transported across cell membranes, so that increasing circulating glutathione levels in blood would facilitate the intracellular uptake of glutathione and alleviate depleted glutathione levels observed in a variety of disease conditions

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Colonic butyrate is actively transported to colonocytes by monocarboxylate transporters, where the majority (~70%) of transported butyrate is used to generate energy via the citric acid cycle

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