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The extender served as the control medium (CON), while treatment groups were supplemented with Nanogreen tea extract (Nano-GTE) at concentrations of 50, 100, 150, and 200 g/mL, respectively

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Additionally, PT-141 may maintain some affinity for MC1R in the skin, promoting melanin synthesis and contributing to skin pigmentation when administered too frequently and at high doses [4]

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This concentration also aligns well with the standard tirzepatide dosing schedule for the early weeks of a protocol