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Such changes could reduce the transamination activity, as suggested by an interference with the formation of diaminovalerate, a proposed metabolic intermediate in this catalytic reaction of GSAAT ( In light of experimental evidence showing the different monomeric and dimeric states of the Cys substitution mutants compared to GSAAT(WT), we propose that Cys168 and Cys190 are cruical for the protein activity and likely function as redox-active residues

For all trials, the primary end point is change from baseline to end of treatment in body weight

Serving size: 1 capsule, Servings per container: 60 Store in a refrigerator out of reach and sight of children

Carnitine Inborn Errors Metabolism Molecules