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Long-term risks are unknown
There is virtually no oversight of off-label drug or device use, which bypasses the consumer-safety and efficacy purpose of FDA approval processes and is nearly impossible to track
Additionally, Epidermal growth factor (EGF)-like proteins stimulates cells to divide by activating members of the EGF receptor ( EGFR ) family
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Research indicates that cells respond to stiffness gradients through a process called durotaxis (from Latin durus meaning hard and Greek taxis meaning arrangement), initially observed using fibroblasts [82]
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