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3) circularity [4(area)/(perimeter 2 )]

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Nobiletin, functioning as a P-gp inhibitor, can suppress P-gp overexpression in lymphocytes in the AIA rat model when co-administered through a nanodelivery system, providing novel insights for refractory RA (26, 198)

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a method for raising circulating levels of glutathione to achieve clinically beneficial effects includes orally administering one or more doses of delayed-release S-acetyl-glutathione to an individual in need thereof