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Most studies to date involve animal models or pilot human trials , with ongoing investigations into dosing, safety, and therapeutic applications

For example, QTL mapping identified multiple loci for charcoal rot resistance across field environments and proposed candidate disease-response genes (Wang et al

GABA provides an additional layer of protection

DN imposes substantial costs due to increased healthcare utilization, lost productivity, and decreased quality of life

These preclinical results were supported by genome-wide association studies, which have identified variants with reduced activity at the human GIP receptor locus that are associated with reduced BMI [72]

Vit E influences the differentiation and proliferation of immune system T-cells through an indirect mechanism in interleukin IL-2 [47]