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The colon will eventually revert to its original pinkish colour 3 to 6 months after stopping the laxatives

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Bremelanotide, or PT-141, is another distinct melanocortin agonist developed from this research area

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doi: 10.1038/nrrheum.2011.207 Summary Keywords gout, bile acid metabolism, uric acid homeostasis, NLRP3 inflammasome, gut-joint axis, FXR antagonists Citation Sun H, Yang L, Sun Y, Zhang X, Sun X, Zhao X, Sun H, Zhang Q, Yan G and Wang X (2025) Dysregulated bile acid metabolism as a novel player in gout progression: emerging therapeutic strategies