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More participants in the semaglutide group than in the placebo group achieved weight reductions of 5% or more (86% of participants vs 32%), 10% or more (69% vs 12%) and 15% or more (51% vs 5%) at week 68

Administered as a subcutaneous injectable or a nasal spray

Metab Clin Exp 60(9):13251333

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Implication: research supports coaching for weight loss adherence