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Clinicians should: Monitor renal function if severe gastrointestinal adverse effects lead to dehydration Educate patients about symptoms of pancreatitis and the need for immediate medical attention Review concomitant medications that may increase hypoglycaemia risk Be aware that rodent studies showed C-cell thyroid tumours, though human relevance is unknown

This included Matthias Tschp (figure 39), a German who completed a medical degree at Ludwig Maximilian University of Munich in 1993 and then worked as a clinician in neuroendocrinology before taking up a research fellowship at Eli Lilly Discovery Research Laboratories in 1999 to gain expertise in drug discovery and development

They lost 445,000 Medicare Advantage members and expect to lose up to 550,000 by the end of 2025