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Moreover, Nrf2a key regulator of iron homeostasisis robustly activated by BL (Yao et al., 2020a,b), leading to increased production of NAD(P)H-dependent enzymes such as NQO1, suppression of NF-B signaling, and reduction of both -Syn aggregation and oxidative stressmediated neuroinflammatory damage (Lastres-Becker et al., 2016

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Maternal therapy with ASHMI (4.5 mg/mouse twice daily) was more effective than dexamethasone at decreasing offspring susceptibility to airway disease, characterized by increased IgG2a and decreased BALF C-X-C motif chemokine ligand-1 and eotaxin-1 levels [102]

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10.1016/j.ceb.2010.10.012 Curr Opin Cell Biol