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Both are prescription medications and both require clinical evaluation before use

In clinical trials, it has been shown to reduce the severity of symptoms and the risk of heart failure and other major adverse cardiovascular events

In a multicenter randomized trial, NAC combined with metformin improved liver measures in non-alcoholic steatohepatitis over several months, supporting its role as an add-on to standard care rather than a replacement.[3]NAC in NASH Randomized Trial PubMed View source A more recent double-blind trial in metabolic-associated fatty liver disease also reported improvements in liver function and metabolic markers with NAC, adding to the promising but still-developing evidence base.[4]NAC on Liver Function in MASLD RCT PubMed View source Liver enzymes: modest ALT and AST reductions in trials

Additionally, supplements containing glutathione precursors, such as N-acetylcysteine (NAC) and alpha-lipoic acid, can support the body's natural production of this essential antioxidant