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Ozempic is a prescription medication that contains semaglutide, a synthetic compound designed to mimic the effects of a natural hormone called glucagon-like peptide-1 (GLP-1)

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Mechanistic Interpretation The study identifies a dual immunosuppressive role for IGF-1 in prostate cancer: Antigen presentation impairment: IGF-1 disrupts peptide transport and processing (via TAP1/2, ERAP1, 2M downregulation), reducing surface MHC-I expression and impairing CD8 T-cell recognition

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