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It is important to note that two of the lesions identified did not have a dark color as reported by Buchner et al.;2 both of them were diagnosed as intramucosal nevus

C at position 677 (leading to an alanine at amino acid 222) is the reference allele

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Patient Safety Continuing appetite-suppressing medication at very low BMIs may increase the risk of: Excessive or unintended weight loss Nutritional deficiencies Lean muscle loss Hormonal disruption Disordered eating patterns The BMI 22 kg/m threshold acts as a safety boundary

A thorough medical evaluation is the only way to know if it is a safe and appropriate option for you