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The peroxisome proliferator-activated receptor gamma (PPAR) pathway-which regulates macrophage polarizationis suppressed, further favoring M1 polarization (95, 96)

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Summary Keywords body composition, GLP-1 receptor agonists, gutbrain axis, lean mass preservation, postbiotics, resistance training, short-chain fatty acids, weight regain Citation Cengiz Kaynakc E (2026) Potential role of postbiotics in supporting lean mass preservation and weight-loss sustainability during GLP-1based anti-obesity therapy

Moderate Exercise Engaging in gentle movement, such as walking , helps promote blood circulation and lymphatic drainage , which can reduce swelling and prevent fluid or tissue from hardening into lumps