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On the other hand, the use of animal models to study invasive meningococcal disease, in addition to presenting the obvious difficulties in investigating aspects of the extracellular/intracellular phase of meningococcal infection, is hampered by the fact that meningococcus has a very narrow host specificity, essentially restricted to humans

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Groups of 24 - 37 female CD-1 mice each received, intraveneously, doses of 0, 75, or 150 mg ethylene oxide (purity not stated)/kg body weight in an aqueous dextrose solution on days 4 - 6, 6 - 8, 8 - 10, or 10 - 12 of pregnancy

These two medications have become popular because they have shown significant results in helping people lose weight

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