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93 In a randomized placebo-controlled trial that included 99 NASH patients, liver biopsies showed 22.4% of those treated with 700 mg silymarin three times daily for 48 weeks had a reduction in fibrosis versus only 6% who received placebo

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A lower dose of insulin or insulin secretagogue may be required to minimize the risk of hypoglycemia when used in combination with JANUMET XR [see Drug Interactions (7)]

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Nevertheless, the protocol for the present analysis was also reviewed and approved by the Institutional Review Board of Chi Mei Medical Center, Tainan, Taiwan (approval No