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This concept by no means is incompatible with the finding that inhibition of GCGR signalling also results in alpha cell proliferation but we emphasise that the latter effect operates on a much longer time scale than the acute effect we now describe (days/weeks rather than minutes/hours)

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Nature (2017) 550:2559

Be aware that switching between medications typically means starting the new one at a low dose regardless of where you were on the previous medication