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Introduction and research framework Epithalon (also known as Epitalon, Epithalone or AGAG) is a synthetic tetrapeptide consisting of four amino acids that was developed by Russian scientist Professor Vladimir Khavinson at the Institute of Bioregulation and Gerontology in Saint Petersburg

Researchers hypothesize that the elevated NAD+ levels increase futile cycling a process where cells burn energy to maintain electrochemical gradients rather than storing it as lipid droplets

M2 microglia and macrophages drive oligodendrocyte differentiation during CNS remyelination