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NICE-recommended weight management strategies include: Dietary intervention aiming for a 600 kcal/day deficit through reduced portion sizes, limiting energy-dense foods, and increasing fruit and vegetable consumption Physical activity building up to 150300 minutes of moderate-intensity aerobic activity weekly, plus muscle-strengthening activities on at least two days weekly, in line with UK Chief Medical Officers' guidelines [10] Behavioural approaches including self-monitoring, goal-setting, and addressing emotional eating patterns Commercial weight management programmes such as those meeting NICE quality standards (QS127) Very-low-calorie diets in specific circumstances, under clinical supervision and for limited periods For patients with a BMI 30 kg/m (or 27.5 kg/m in those of South Asian, Chinese, or other Asian family origin) who have not achieved adequate weight loss through lifestyle measures alone, pharmacological interventions may be considered

Brunt EM, Wong VW, Nobili V, et al

A psychiatrist or physician can provide proper diagnosis, rule out medical causes of mood symptoms, monitor for drug interactions with existing medications, and adjust treatment plans based on response

Led by Aloni Le, DNP, ARNP, FNP-C , a Board-Certified Nurse Practitioner with more than 13 years of advanced medical experience, our treatments are carefully designed to deliver what your body needs safely and effectively

Corresponding author Mohamad Nassereddine, MD, Division of Orthopedic Surgery, American University of Beirut Medical Center, Beirut, Lebanon Email: [email protected]

CagriSema (cagrilintide + semaglutide) reached 20.4% in the same trial