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That suggests the system is actively adapting to defend the new body weight. These metabolic shifts may help explain why weight loss eventually plateaus despite continued drug treatmentand why weight regain can occur so rapidly once treatment stops

This pricing dynamic constrains overall market penetration and slows adoption despite the strong clinical benefits of GLP-1 therapies in weight management and glycemic control, making cost a key obstacle to broader global uptake

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doi: 10.1039/D2SC00676F 164 LiHDingPPengBMingY-ZJHInternationalPD

Neurodermatitis : Causes intensely itchy patches, often triggered by stress or anxiety

It is a safety issue