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Neuroprotective effects of the novel GLP-1 long acting analogue semaglutide in the MPTP Parkinson's disease mouse model

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[4] [1] Beyond their metabolic effects, GLP-1 receptors are widely distributed throughout the central nervous system, particularly in brain regions involved in reward processing, appetite regulation, and addictive behaviours

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Nature 496(7443):101105 Sourbier C, Ricketts CJ, Liao PJ et al (2019) Proteasome inhibition disrupts the metabolism of fumarate hydratase- deficient tumors by downregulating p62 and c-Myc