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The framework balances two equal goals: - Preventing organ dysfunction in those without complications by targeting fat mass accumulation - Reversing organ dysfunction in patients with complications such as type 2 diabetes, cardiovascular disease, MASLD, heart failure, or osteoarthritis This approach positions obesity treatment as disease modification, emphasizing protection of the heart, liver, pancreas, joints, and lungs beyond weight reduction alone EASO Framework: #EASO #Tirzepatide #Semaglutide #GLP1RAs #Getzpharma To view or add a comment, sign in Chronic kidney disease (CKD) is highly heterogeneous with different etiologies and mechanisms believed to underlie diabetic kidney disease (DKD), glomerulonephritis (GN), and hypertensive nephropathy (HTN)

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doi:10.3945/ajcn.111.016600

Inflammatory proteins associated with Alzheimers disease reduced by a GLP1 receptor agonist: A post hoc analysis of the EXSCEL randomized placebo controlled trial

Researchers tracking their before and after results typically notice measurable changes beginning during this phase