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By reducing impulsivity and enhancing prefrontal cortex activity, GLP-1 drugs may strengthen the brains ability to override compulsive urges the I know I shouldnt, but I cant stop experience that defines so much of active addiction

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Scientists originally developed them to treat type 2 diabetes, but research shows they also promote weight loss when paired with healthy habits

This prevents the needle from reaching muscle tissue, which changes absorption characteristics and increases pain

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(NEJM, 2023) reported that gastrointestinal adverse events were the dominant tolerability signal across all retatrutide arms and scaled steeply with the size of each escalation step [2][5]