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Compared to pioglitazone treatment, rosiglitazone increases the risk of AMI and heart failure in type 2 diabetic patients and elderly patients [222,223,224]

they play key roles in the regulation of three physiological processes: Blood coagulation: prothrombin (factor II), factors VII, IX, and X, and proteins C, S, and Z [50] Bone metabolism: osteocalcin, matrix Gla protein (MGP), [51] periostin, [52] and Gla-rich protein

Allogeneic blood stem cell transplantation for refractory leukemia and lymphoma: potential advantage of blood over marrow allografts

Recent studies also suggest that glycemic variabilityfluctuations in glucose levelsmay be as important as mean glycemia in predicting adverse renal outcomes