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The mechanism behind the better female response to weight reduction remains unclear, but it could potentially be associated with increased drug exposure observed in women, possibly due to their lower average body weight [57]
If youre concerned about how the medication might affect your appetite or experience any mild side effects, such as nausea, having a light meal beforehand might help alleviate any discomfort
CrossRef Hepatic steatosis index for prediction of metabolic dysfunctionassociated steatotic liver disease (MASLD) among young Indian women with gestational diabetes and normoglycaemia during index pregnancy Alpesh Goyal, Suraj Kubihal, Yashdeep Gupta, Shalimar, Devasenathipathy Kandasamy, Mani Kalaivani, Nikhil Tandon Diabetes, Obesity and Metabolism .2025
The ratio of target-receptor agonism can be manipulated to maximise efficacy whilst optimising adverse effects [31]